PPARɣ drives IL-33-dependent ILC2 pro-tumoral functions

Group 2 innate lymphoid cells (ILC2s) play a critical role in protection against helminths and in diverse inflammatory diseases by responding to soluble factors such as the alarmin IL-33, that is often overexpressed in cancer. Nonetheless, regulatory factors that dictate ILC2 functions remain poorly...

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Publicado en:Nat Commun
Autores principales: Ercolano, Giuseppe, Gomez-Cadena, Alejandra, Dumauthioz, Nina, Vanoni, Giulia, Kreutzfeldt, Mario, Wyss, Tania, Michalik, Liliane, Loyon, Romain, Ianaro, Angela, Ho, Ping-Chih, Borg, Christophe, Kopf, Manfred, Merkler, Doron, Krebs, Philippe, Romero, Pedro, Trabanelli, Sara, Jandus, Camilla
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2021
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8100153/
https://ncbi.nlm.nih.gov/pubmed/33953160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-22764-2
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