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IL-33 is produced by colon fibroblasts and differentially regulated in acute and chronic murine colitis

IL-33 is upregulated in ulcerative colitis and has a protective role in chemically-induced acute murine colitis. We aimed to determine whether IL-33 influences Il10(−/−) chronic colitis and its cellular source in health and during colitis. Il10(−/−)Il33(−/−) and Il10(−/−)Il33(+/+) littermates develo...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Waddell, Amanda, Vallance, Jefferson E., Fox, Sejal, Rosen, Michael J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8100152/
https://ncbi.nlm.nih.gov/pubmed/33953267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-89119-1
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