KCNQ Channels in the Mesolimbic Reward Circuit Regulate Nociception in Chronic Pain in Mice

Mesocorticolimbic dopaminergic (DA) neurons have been implicated in regulating nociception in chronic pain, yet the mechanisms are barely understood. Here, we found that chronic constructive injury (CCI) in mice increased the firing activity and decreased the KCNQ channel-mediated M-currents in vent...

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Veröffentlicht in:Neurosci Bull
Hauptverfasser: Wang, Hao-Ran, Hu, Su-Wan, Zhang, Song, Song, Yu, Wang, Xiao-Yi, Wang, Lei, Li, Yang-Yang, Yu, Yu-Mei, Liu, He, Liu, Di, Ding, Hai-Lei, Cao, Jun-Li
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Singapore 2021
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8099961/
https://ncbi.nlm.nih.gov/pubmed/33900570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12264-021-00668-x
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