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Deep generative model embedding of single-cell RNA-Seq profiles on hyperspheres and hyperbolic spaces

Single-cell RNA-Seq (scRNA-seq) is invaluable for studying biological systems. Dimensionality reduction is a crucial step in interpreting the relation between cells in scRNA-seq data. However, current dimensionality reduction methods are often confounded by multiple simultaneous technical and biolog...

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Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Ding, Jiarui, Regev, Aviv
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8099904/
https://ncbi.nlm.nih.gov/pubmed/33953202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-22851-4
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