Capecitabine plus temozolomide in patients with grade 3 unresectable or metastatic gastroenteropancreatic neuroendocrine neoplasms with Ki-67 index <55%: single-arm phase II study

BACKGROUND: Grade 3 neuroendocrine neoplasms (NENs) of gastroenteropancreatic (GEP) origin with Ki-67 indices <55% do not respond well to platinum-based chemotherapy. The combination of capecitabine and temozolomide (CAPTEM) has shown favorable responses in grade 1-2 NENs, but has rarely been stu...

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Detalhes bibliográficos
Publicado no:ESMO Open
Main Authors: Jeong, H., Shin, J., Jeong, J.H., Kim, K.-p., Hong, S.-M., Kim, Y.-i., Ryu, J.-S., Ryoo, B.-Y., Yoo, C.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8099746/
https://ncbi.nlm.nih.gov/pubmed/33901869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.esmoop.2021.100119
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