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Syndecan-1 downregulates syndecan-4 expression by suppressing the ERK1/2 and p38 MAPK signaling pathways in cultured vascular endothelial cells

Syndecan-1 and syndecan-4 are members of the syndecan family of transmembrane heparan sulfate proteoglycans. Vascular endothelial cells synthesize both species of proteoglycans and use them to regulate the blood coagulation-fibrinolytic system and their proliferation via their heparin-like activity...

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Veröffentlicht in:Biochem Biophys Rep
Hauptverfasser: Hara, Takato, Sato, Arisa, Yamamoto, Chika, Kaji, Toshiyuki
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8099740/
https://ncbi.nlm.nih.gov/pubmed/33997316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2021.101001
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