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CD11b Deficiency Exacerbates Methicillin-Resistant Staphylococcus aureus-Induced Sepsis by Upregulating Inflammatory Responses of Macrophages

Macrophages are important for the first line of defense against microbial pathogens. Integrin CD11b, which is encoded by Itgam, is expressed on the surface of macrophages and has been implicated in adhesion, migration, and cell-mediated cytotoxicity. However, the functional impact of CD11b on the in...

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Detalhes bibliográficos
Publicado no:Immune Netw
Main Authors: Sim, Hyunsub, Jeong, Daecheol, Kim, Hye-In, Pak, Seongwon, Thapa, Bikash, Kwon, Hyung-Joo, Lee, Keunwook
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Association of Immunologists 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8099615/
https://ncbi.nlm.nih.gov/pubmed/33996169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4110/in.2021.21.e13
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