Oxidative damage to hyaluronan–CD44 interactions as an underlying mechanism of action of oxidative stress-inducing cancer therapy

Multiple cancer therapies nowadays rely on oxidative stress to damage cancer cells. Here we investigated the biological and molecular effect of oxidative stress on the interaction between CD44 and hyaluronan (HA), as interrupting their binding can hinder cancer progression. Our experiments demonstra...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Yusupov, Maksudbek, Privat-Maldonado, Angela, Cordeiro, Rodrigo M., Verswyvel, Hanne, Shaw, Priyanka, Razzokov, Jamoliddin, Smits, Evelien, Bogaerts, Annemie
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8099558/
https://ncbi.nlm.nih.gov/pubmed/33895486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2021.101968
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