Development of Perphenazine-Loaded Solid Lipid Nanoparticles: Statistical Optimization and Cytotoxicity Studies

OBJECTIVE: Perphenazine (PPZ), as a typical antipsychotic medical substance, has the same effectiveness compared to atypical antipsychotic medications for the treatment of schizophrenia. Despite the lipophilic essence, PPZ encounters limited bioavailability caused by the first-pass metabolism follow...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Farsani, Parisa Abbasi, Mahjub, Reza, Mohammadi, Mojdeh, Oliaei, Seyed Sajad, Mahboobian, Mohammad Mehdi
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8099510/
https://ncbi.nlm.nih.gov/pubmed/33997026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2021/6619195
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