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The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis

TRIM9 and TRIM67 are neuronally enriched E3 ubiquitin ligases essential for appropriate morphogenesis of cortical and hippocampal neurons and fidelitous responses to the axon guidance cue netrin-1. Deletion of murine Trim9 or Trim67 results in neuroanatomical defects and striking behavioral deficits...

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Pubblicato in:Mol Biol Cell
Autori principali: Menon, Shalini, Goldfarb, Dennis, Ho, Chris T., Cloer, Erica W., Boyer, Nicholas P., Hardie, Christopher, Bock, Andrew J., Johnson, Emma C., Anil, Joel, Major, M. Ben, Gupton, Stephanie L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8098814/
https://ncbi.nlm.nih.gov/pubmed/33378226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E20-10-0622
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