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The CAG/Polyglutamine Tract Diseases: Gene Products and Molecular Pathogenesis

In the past few years, a new type of genetic mutation, expansion of trinucleotide repeats, has been shown to cause neurologic disease. This new class of mutations was first identified in 1991 as the underlying genetic defect in spinal and bulbar muscular atrophy and the fragile X syndrome, and in re...

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Detalles Bibliográficos
Publicado en:Brain Pathol
Main Authors: Koshy, Beena T., Zoghbi, Huda Y.
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Publishing Ltd 2008
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8098410/
https://ncbi.nlm.nih.gov/pubmed/9217976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.1997.tb00894.x
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