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Deep cerebellar stimulation reduces ataxic motor symptoms in the shaker rat
OBJECTIVE: Degenerative cerebellar ataxias (DCAs) affect up to 1 in 5,000 people worldwide, leading to incoordination, tremor, and falls. Loss of Purkinje cells, nearly universal across DCAs, dysregulates the dentatothalamocortical network. To address the paucity of treatment strategies, we develope...
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| Publicado en: | Ann Neurol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8098166/ https://ncbi.nlm.nih.gov/pubmed/30854718 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.25464 |
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