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Association of EGFR Gene Amplification and CDKN2 (p16/MTS1) Gene Deletion in Glioblastoma Multiforme

Glioblastoma multiforme (GBM) can be divided into genetic subsets: approximately one‐third of GBM, primarily in older adults, have EGFR amplification; another one‐third, primarily in younger adults, have TP53 mutation. The majority of GBM also have homozygous deletions of the CDKN2 (p16/MTS1) gene,...

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Detalhes bibliográficos
Publicado no:Brain Pathol
Main Authors: Hayashi, Yutaka, Ueki, Keisuke, Waha, Andreas, Wiestler, Otmar D., Louis, David N., von Deimlina, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8098131/
https://ncbi.nlm.nih.gov/pubmed/9217972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.1997.tb00890.x
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