Methylated markers accurately distinguish primary central nervous system lymphomas (PCNSL) from other CNS tumors

BACKGROUND: Definitive diagnosis of primary central nervous system lymphoma (PCNSL) requires invasive surgical brain biopsy, causing treatment delays. In this paper, we identified and validated tumor-specific markers that can distinguish PCNSL from other CNS tumors in tissues. In a pilot study, we t...

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Detalhes bibliográficos
Publicado no:Clin Epigenetics
Main Authors: Downs, Bradley M., Ding, Wanjun, Cope, Leslie M., Umbricht, Christopher B., Li, Wenge, He, Huihua, Ke, Xiaokang, Holdhoff, Matthias, Bettegowda, Chetan, Tao, Weiping, Sukumar, Saraswati
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8097855/
https://ncbi.nlm.nih.gov/pubmed/33952317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-021-01091-9
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