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Progress towards an inducible, replication-proficient transposon delivery vector for Chlamydia trachomatis

Background Genetic systems have been developed for Chlamydia but the extremely low transformation frequency remains a significant bottleneck.  Our goal is to develop a self-replicating transposon delivery vector for C. trachomatis which can be expanded prior to transposase induction. Methods We made...

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Detalles Bibliográficos
Publicado en:Wellcome Open Res
Autores principales: Skilton, Rachel J., O'Neill, Colette, Thomson, Nicholas R., Lampe, David J., Clarke, Ian N.
Formato: Artigo
Lenguaje:Inglês
Publicado: F1000 Research Limited 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8097735/
https://ncbi.nlm.nih.gov/pubmed/33997299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/wellcomeopenres.16665.1
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