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PBSIM2: a simulator for long-read sequencers with a novel generative model of quality scores

MOTIVATION: Recent advances in high-throughput long-read sequencers, such as PacBio and Oxford Nanopore sequencers, produce longer reads with more errors than short-read sequencers. In addition to the high error rates of reads, non-uniformity of errors leads to difficulties in various downstream ana...

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Publicat a:Bioinformatics
Autors principals: Ono, Yukiteru, Asai, Kiyoshi, Hamada, Michiaki
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8097687/
https://ncbi.nlm.nih.gov/pubmed/32976553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btaa835
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