High-Dose Micafungin in Neonates and Young Infants with Invasive Candidiasis: Results of a Phase 2 Study

Limited data are available on the most appropriate dosing, efficacy, and safety of micafungin in neonates and young infants with invasive candidiasis (IC). This study evaluated plasma levels, efficacy, and safety of micafungin at a dose of 8 mg/kg daily for a mean of 13.3 days (±5.2 days) in 35 neon...

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Bibliographische Detailangaben
Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Auriti, Cinzia, Goffredo, Bianca M., Ronchetti, Maria P., Piersigilli, Fiammetta, Cairoli, Sara, Bersani, Iliana, Dotta, Andrea, Bagolan, Pietro, Pai, Manjunath P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2021
Schlagworte:
Clinical Therapeutics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8097467/
https://ncbi.nlm.nih.gov/pubmed/33558294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02494-20
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