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The Benzimidazole SPR719 Shows Promising Concentration-Dependent Activity and Synergy against Nontuberculous Mycobacteria

Nontuberculous mycobacterial pulmonary disease (NTM-PD) is emerging worldwide. Currently recommended multidrug treatment regimens yield poor outcomes, and new drugs and regimens are direly needed. SPR719, the active moiety of SPR720, is a new benzimidazole antibiotic with limited data on antimycobac...

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Detalles Bibliográficos
Publicado en:Antimicrob Agents Chemother
Main Authors: Pennings, Lian J., Ruth, Mike Marvin, Wertheim, Heiman F. L., van Ingen, Jakko
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8097464/
https://ncbi.nlm.nih.gov/pubmed/33468478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02469-20
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