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Efficient Treatment of Experimental Cerebral Malaria by an Artemisone-SMEDDS System: Impact of Application Route and Dosing Frequency

Artemisone (ART) has been successfully tested in vitro and in animal models against several diseases. However, its poor aqueous solubility and limited chemical stability are serious challenges. We developed a self-microemulsifying drug delivery system (SMEDDS) that overcomes these limitations. Here,...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Zech, Johanna, Salaymeh, Nadeen, Hunt, Nicholas H., Mäder, Karsten, Golenser, Jacob
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8097435/
https://ncbi.nlm.nih.gov/pubmed/33558284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02106-20
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