A Hyaluronic Acid Hydrogel Loaded with Gentamicin and Vancomycin Successfully Eradicates Chronic Methicillin-Resistant Staphylococcus aureus Orthopedic Infection in a Sheep Model

Implantable orthopedic devices have had an enormously positive impact on human health; however, despite best practice, patients are prone to developing orthopedic device-related infections (ODRI) that have high treatment failure rates. One barrier to the development of improved treatment options is...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Boot, Willemijn, Schmid, Tanja, D’Este, Matteo, Guillaume, Olivier, Foster, Andrew, Decosterd, Laurent, Richards, Robert G., Eglin, David, Zeiter, Stephan, Moriarty, Thomas F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2021
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8097416/
https://ncbi.nlm.nih.gov/pubmed/33526492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01840-20
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