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Ub and Dub of RNF43/ZNRF3 in the WNT signalling pathway

The E3 ubiquitin ligases RING finger protein 43 (RNF43) and zinc and RING finger 3 (ZNRF3) have received great attention for their critical role in regulating WNT signalling during adult stem cell homeostasis. By promoting the turnover of WNT receptors, Frizzled and LRP5/6, RNF43 and ZNRF3 ensure th...

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Détails bibliographiques
Publié dans:EMBO Rep
Auteurs principaux: Colozza, Gabriele, Koo, Bon‐Kyoung
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8097353/
https://ncbi.nlm.nih.gov/pubmed/33938624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.202152970
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