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Innate IFN-γ Is Essential for Systemic Chlamydia muridarum Control in Mice, While CD4 T Cell-Dependent IFN-γ Production Is Highly Redundant in the Female Reproductive Tract

Protective immunity against the obligate intracellular bacterium Chlamydia has long been thought to rely on CD4 T cell-dependent gamma interferon (IFN-γ) production. Nevertheless, whether IFN-γ is produced by other cellular sources during Chlamydia infection and how CD4 T cell-dependent and -indepen...

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Dades bibliogràfiques
Publicat a:Infect Immun
Autors principals: Mercado, Miguel A. B., Du, Wuying, Malaviarachchi, Priyangi A., Gann, Jessica I., Li, Lin-Xi
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8097277/
https://ncbi.nlm.nih.gov/pubmed/33257535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00541-20
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