Intranasal Immunization with Acellular Pertussis Vaccines Results in Long-Term Immunity to Bordetella pertussis in Mice

Bordetella pertussis colonizes the respiratory mucosa of humans, inducing an immune response seeded in the respiratory tract. An individual, once convalescent, exhibits long-term immunity to the pathogen. Current acellular pertussis (aP) vaccines do not induce the long-term immune response observed...

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Veröffentlicht in:Infect Immun
Hauptverfasser: Wolf, M. Allison, Boehm, Dylan T., DeJong, Megan A., Wong, Ting Y., Sen-Kilic, Emel, Hall, Jesse M., Blackwood, Catherine B., Weaver, Kelly L., Kelly, Claire O., Kisamore, Caleb A., Bitzer, Graham J., Bevere, Justin R., Barbier, Mariette, Damron, F. Heath
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2021
Schlagworte:
Microbial Immunity and Vaccines
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8097269/
https://ncbi.nlm.nih.gov/pubmed/33318136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00607-20
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