GIPC2 is an endocrine-specific tumor suppressor gene for both sporadic and hereditary tumors of RET- and SDHB-, but not VHL-associated clusters of pheochromocytoma/paraganglioma

Pheochromocytoma/paraganglioma (PPGL) is an endocrine tumor of the chromaffin cells in the adrenal medulla or the paraganglia. Currently, about 70% of PPGLs can be explained by germline or somatic mutations in several broadly expressed susceptibility genes including RET, VHL, and SDHB, while for the...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Dong, Yeqing, Huang, Yongsheng, Fan, Chengyan, Wang, Liang, Zhang, Ran, Li, Wenhua, Guo, Zhengguang, Wang, Dong, Zheng, Zhi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8096975/
https://ncbi.nlm.nih.gov/pubmed/33947839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03731-7
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