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Dynamically elongated associative toehold for tuning DNA circuit kinetics and thermodynamics
Associative toehold is a powerful concept enabling efficient combinatorial computation in DNA circuit. A longer association length boosts circuit kinetics and equilibrium signal but results in higher leak rate. We reconcile this trade-off by using a hairpin lock design to dynamically elongate the ef...
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| Publicado en: | Nucleic Acids Res |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2021
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8096276/ https://ncbi.nlm.nih.gov/pubmed/33849054 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab212 |
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