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The Genome-wide Methylation Profile of CD4(+) T Cells From Individuals With Human Immunodeficiency Virus (HIV) Identifies Distinct Patterns Associated With Disease Progression

BACKGROUND: Human genetic variation—mostly in the human leukocyte antigen (HLA) and C–C chemokine receptor type 5 (CCR5) regions—explains 25% of the variability in progression of human immunodeficiency virus (HIV) infection. However, it is also known that viral infections can modify cellular DNA met...

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Detalhes bibliográficos
Publicado no:Clin Infect Dis
Main Authors: Moron-Lopez, Sara, Urrea, Victor, Dalmau, Judith, Lopez, Miguel, Puertas, Maria C, Ouchi, Dan, Gómez, Antonio, Passaes, Caroline, Mothe, Beatriz, Brander, Christian, Saez-Cirion, Asier, Clotet, Bonaventura, Esteller, Manel, Berdasco, Maria, Martinez-Picado, Javier
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8096268/
https://ncbi.nlm.nih.gov/pubmed/32712664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/ciaa1047
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