The rDNA is biomolecular condensate formed by polymer–polymer phase separation and is sequestered in the nucleolus by transcription and R-loops

The nucleolus is the site of ribosome biosynthesis encompassing the ribosomal DNA (rDNA) locus in a phase separated state within the nucleus. In budding yeast, we find the rDNA locus and Cdc14, a protein phosphatase that co-localizes with the rDNA, behave like a condensate formed by polymer–polymer...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Nucleic Acids Res
Asıl Yazarlar: Lawrimore, Josh, Kolbin, Daniel, Stanton, John, Khan, Muznah, de Larminat, Solenn C, Lawrimore, Colleen, Yeh, Elaine, Bloom, Kerry
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2021
Konular:
Molecular Biology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8096216/
https://ncbi.nlm.nih.gov/pubmed/33836082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab229
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