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Amoeboid Microglia in the Periventricular White Matter Induce Oligodendrocyte Damage through Expression of Proinflammatory Cytokines via MAP Kinase Signaling Pathway in Hypoxic Neonatal Rats

Hypoxic injury in the perinatal period results in periventricular white matter (PWM) lesions with axonal damage and oligodendroglial loss. It also alters macrophage function by perpetuating expression of inflammatory mediators. Relevant to this is the preponderance of amoeboid microglial cells (AMC)...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Brain Pathol
Hauptverfasser: Deng, YiYu, Lu, Jia, Sivakumar, Viswanathan, Ling, Eng Ang, Kaur, Charanjit
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Publishing Ltd 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8095524/
https://ncbi.nlm.nih.gov/pubmed/18371179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2008.00138.x
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