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Estimating the Efficiency Gain of Covariate-Adjusted Analyses in Future Clinical Trials Using External Data

We present a general framework for using existing data to estimate the efficiency gain from using a covariate-adjusted estimator of a marginal treatment effect in a future randomized trial. We describe conditions under which it is possible to define a mapping from the distribution that generated the...

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Détails bibliographiques
Publié dans:ArXiv
Auteurs principaux: Li, Xiudi, Li, Sijia, Luedtke, Alex
Format: Artigo
Langue:Inglês
Publié: Cornell University 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8095209/
https://ncbi.nlm.nih.gov/pubmed/33948450
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