Activity of blinatumomab in lymphoblastic leukemia with impaired T-cell immunity due to congenital immunodeficiency

Blinatumomab, a single-chain, bispecific, T-cell–engaging antibody targeting CD19, is effective in B-precursor acute lymphoblastic leukemia (BCP-ALL), even in the context of chemotherapy-related partial T-cell immunodeficiency. We report 2 patients with BCP-ALL and congenital T-cell immunodeficiency...

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Dettagli Bibliografici
Pubblicato in:Blood Adv
Autori principali: Ramdeny, Sandheeah, Chaudhary, Asima, Worth, Austen, Ghorashian, Sara, Slatter, Mary, Lum, Su Han, Vora, Ajay
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2021
Soggetti:
Exceptional Case Report
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8095136/
https://ncbi.nlm.nih.gov/pubmed/33881461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2021004284
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