Pentoxifylline improves the survival of spermatogenic cells via oxidative stress suppression and upregulation of PI3K/AKT pathway in mouse model of testicular torsion-detorsion

Testicular torsion-detorsion results in enhanced formation of free radicals which contribute to the pathophysiology of testicular tissue damage. Recent reports have identified protective role of pentoxifylline (PTX) against free radicals. Thus, we determined the protective effect of pentoxifylline a...

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Detalhes bibliográficos
Publicado no:Heliyon
Main Authors: Dhulqarnain, Akanji Omotosho, Takzaree, Nasrin, Hassanzadeh, Golamreza, Tooli, Heidar, Malekzadeh, Mehrnoush, Khanmohammadi, Nasrin, Yaghobinejad, Mahsa, Solhjoo, Somayeh, Rastegar, Tayebeh
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8095127/
https://ncbi.nlm.nih.gov/pubmed/33997400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heliyon.2021.e06868
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