miR-1283 Contributes to Endoplasmic Reticulum Stress in the Development of Hypertension Through the Activating Transcription Factor-4 (ATF4)/C/EBP-Homologous Protein (CHOP) Signaling Pathway

BACKGROUND: Hypertension-related microRNA(miR)-1283 and its target gene, activating transcription factor-4 (ATF4), can regulate vascular endothelial dysfunction. This study aimed to explore whether miR-1283 prevents hypertension through targeting ATF4. MATERIAL/METHODS: Transcriptome sequencing was...

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Detalles Bibliográficos
Publicado en:Med Sci Monit
Main Authors: Chen, Weihao, Liu, Tianhao, Liang, Qiuer, Chen, Xudong, Tao, Wencong, Fang, Meixia, Xiao, Ya, Chen, Liguo
Formato: Artigo
Idioma:Inglês
Publicado: International Scientific Literature, Inc. 2021
Assuntos:
Animal Study
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8095088/
https://ncbi.nlm.nih.gov/pubmed/33911065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.930552
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