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Substantial Attenuation of Virulence of Tembusu Virus Strain PS Is Determined by an Arginine at Residue 304 of the Envelope Protein

The Tembusu virus (TMUV) PS strain, derived by several passages and plaque purifications in BHK-21 cells, displays markedly lower virulence in Pekin ducklings relative to a natural isolate of TMUV, but the potential virulence determinants and the in vivo mechanisms for substantial virulence attenuat...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Yang, Lixin, Liang, Te, Lv, Junfeng, Qu, Shenghua, Meng, Runze, Yang, Baolin, Feng, Chonglun, Dai, Weiqian, Wang, Xiaoyan, Zhang, Bing, Zhang, Dabing
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8094961/
https://ncbi.nlm.nih.gov/pubmed/33328312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02331-20
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