Fowl Adenovirus Serotype 4 Induces Hepatic Steatosis via Activation of Liver X Receptor-α

Fowl adenovirus serotype 4 (FAdV-4) is a hepatotropic virus that causes severe hepatic damage characterized by basophilic intranuclear inclusion bodies, vacuolar degeneration, and multifocal necrosis in hepatocytes. Many aspects of FAdV-4 infection and pathogenesis, however, remain unknown. Here, we...

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Bibliographic Details
Published in:J Virol
Main Authors: Yuan, Feng, Hou, Lei, Wei, Li, Quan, Rong, Wang, Jing, Liu, Hao, Liu, Jue
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2021
Subjects:
Cellular Response to Infection
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8094942/
https://ncbi.nlm.nih.gov/pubmed/33361420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01938-20
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