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Plasmacytoid Dendritic Cells Mediate Control of Ross River Virus Infection via a Type I Interferon-Dependent, MAVS-Independent Mechanism

Ross River virus (RRV) is a mosquito-borne alphavirus that causes epidemics of debilitating musculoskeletal disease. To define the innate immune mechanisms that mediate control of RRV infection, we studied a RRV strain encoding 6 nonsynonymous mutations in nsP1 (RRV-T48-nsP1(6M)) that is attenuated...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Haist, Kelsey C., Carpentier, Kathryn S., Davenport, Bennett J., Morrison, Thomas E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8094935/
https://ncbi.nlm.nih.gov/pubmed/33361425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01538-20
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