Tauroursodeoxycholic acid prevents Burkholderia pseudomallei-induced endoplasmic reticulum stress and is protective during melioidosis in mice

BACKGROUND: Burkholderia pseudomallei, a facultative intracellular bacterium, is the aetiological agent of melioidosis that is responsible for up to 40% sepsis-related mortality in epidemic areas. However, no effective vaccine is available currently, and the drug resistance is also a major problem i...

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Bibliografiske detaljer
Udgivet i:BMC Microbiol
Main Authors: Yuan, Siqi, Fang, Yao, Tang, Mengling, Hu, Zhiqiang, Rao, Chenglong, Chen, Jiangao, Xia, Yupei, Zhang, Meijuan, Yan, Jingmin, Tang, Bin, He, Xiaoyi, Xie, Jianping, Mao, Xuhu, Li, Qian
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2021
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8094575/
https://ncbi.nlm.nih.gov/pubmed/33947331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12866-021-02199-x
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