Reduction in the Motoneuron Inhibitory/Excitatory Synaptic Ratio in an Early‐Symptomatic Mouse Model of Amyotrophic Lateral Sclerosis

Excitotoxicity is a widely studied mechanism underlying motoneuron degeneration in amyotrophic lateral sclerosis (ALS). Synaptic alterations that produce an imbalance in the ratio of inhibitory/excitatory synapses are expected to promote or protect against motoneuron excitotoxicity. In ALS patients,...

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Detalhes bibliográficos
Publicado no:Brain Pathol
Main Authors: Sunico, Carmen R., Domínguez, Germán, García‐Verdugo, José Manuel, Osta, Rosario, Montero, Fernando, Moreno‐López, Bernardo
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2010
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8094302/
https://ncbi.nlm.nih.gov/pubmed/20653686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2010.00417.x
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