Nucleolar Disruption and Cajal Body Disassembly are Nuclear Hallmarks of DNA Damage‐Induced Neurodegeneration in Purkinje Cells

The Purkinje cell (PC) degeneration (pcd) phenotype results from mutation in nna1 gene and is associated with the degeneration and death of PCs during the postnatal life. Although the pcd mutation is a model of the ataxic mouse, it shares clinical and pathological characteristics of inherited human...

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Detalhes bibliográficos
Publicado no:Brain Pathol
Main Authors: Baltanás, Fernando C., Casafont, Iñigo, Weruaga, Eduardo, Alonso, José R., Berciano, María T., Lafarga, Miguel
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2010
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8094285/
https://ncbi.nlm.nih.gov/pubmed/21054627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2010.00461.x
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