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Widespread Proliferation Impairment and Hypocellularity in the Cerebellum of Fetuses with Down Syndrome

Evidence in mouse models for Down syndrome (DS) and human fetuses with DS clearly shows severe neurogenesis impairment in various telencephalic regions, suggesting that this defect may underlie the cognitive abnormalities of DS. As cerebellar hypotrophy and motor disturbances are part of the clinica...

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Detalhes bibliográficos
Publicado no:Brain Pathol
Main Authors: Guidi, Sandra, Ciani, Elisabetta, Bonasoni, Paola, Santini, Donatella, Bartesaghi, Renata
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8094247/
https://ncbi.nlm.nih.gov/pubmed/21040072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2010.00459.x
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