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Kaempferol Regulates the Expression of Airway MUC5AC Mucin Gene via IκBα-NF-κB p65 and p38-p44/42-Sp1 Signaling Pathways

In the present study, kaempferol, a flavonoidal natural compound found in Polygonati Rhizoma, was investigated for its potential effect on the gene expression and production of airway MUC5AC mucin. A human respiratory epithelial NCI-H292 cells was pretreated with kaempferol for 30 min and stimulated...

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Detalhes bibliográficos
Publicado no:Biomol Ther (Seoul)
Main Authors: Li, Xin, Jin, Fengri, Lee, Hyun Jae, Lee, Choong Jae
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Society of Applied Pharmacology 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8094069/
https://ncbi.nlm.nih.gov/pubmed/33281120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4062/biomolther.2020.149
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