Long‐term response to osimertinib in elderly patients with lung adenocarcinoma harbouring de novo EGFR T790M: a case report and literature review

Osimertinib is a potent and irreversible epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) that selectively acts on both EGFR‐sensitive and EGFR T790M‐resistant mutations. Patients with pre‐treatment EGFR T790M mutations (de novo EGFR T790M) respond poorly to existing EGFR‐TKIs...

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Bibliografiske detaljer
Udgivet i:Respirol Case Rep
Main Authors: Sumi, Toshiyuki, Kamada, Koki, Shijubou, Naoki, Yamada, Yuichi, Nakata, Hisashi, Mori, Yuji, Chiba, Hirofumi
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley & Sons, Ltd 2021
Fag:
Case Reports
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8094050/
https://ncbi.nlm.nih.gov/pubmed/33976888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/rcr2.759
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