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Recent advances in the understanding of the molecular pathogenesis and targeted therapy options in Langerhans cell histiocytosis
Langerhans cell histiocytosis (LCH) is the most common histiocytic disorder caused by the clonal expansion of myeloid precursors that differentiate into CD1a+/CD207+ cells in the lesion. Advances in genomic sequencing techniques have improved our understanding of the pathophysiology of LCH. Activati...
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| Published in: | Blood Res |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Korean Society of Hematology; Korean Society of Blood and Marrow Transplantation; Korean Society of Pediatric Hematology-Oncology; Korean Society on Thrombosis and Hemostasis
2021
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8093998/ https://ncbi.nlm.nih.gov/pubmed/33935037 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5045/br.2021.2021013 |
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