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Dysregulation of LINC00470 and METTL3 promotes chemoresistance and suppresses autophagy of chronic myelocytic leukaemia cells

Cytoplasmic lncRNAs have been found to directly interact with target mRNAs and regulate their stability. In this study, we aimed to study the molecular mechanism underlying the function of m(6)A as a central regulator in chemoresistance and CML proliferation. In this study, we established three mice...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Lai, Xun, Wei, Jia, Gu, Xue‐zhong, Yao, Xiang‐mei, Zhang, Di‐si, Li, Feng, Sun, Yun‐yan
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8093980/
https://ncbi.nlm.nih.gov/pubmed/33749070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.16478
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