FYCO1 Regulates Cardiomyocyte Autophagy and Prevents Heart Failure Due to Pressure Overload In Vivo

Autophagy is a cellular degradation process that has been implicated in diverse disease processes. The authors provide evidence that FYCO1, a component of the autophagic machinery, is essential for adaptation to cardiac stress. Although the absence of FYCO1 does not affect basal autophagy in isolate...

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Bibliografische gegevens
Gepubliceerd in:JACC Basic Transl Sci
Hoofdauteurs: Kuhn, Christian, Menke, Maja, Senger, Frauke, Mack, Claudia, Dierck, Franziska, Hille, Susanne, Schmidt, Inga, Brunke, Gabriele, Bünger, Pia, Schmiedel, Nesrin, Will, Rainer, Sossalla, Samuel, Frank, Derk, Eschenhagen, Thomas, Carrier, Lucie, Lüllmann-Rauch, Renate, Rangrez, Ashraf Yusuf, Frey, Norbert
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2021
Onderwerpen:
Preclinical Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8093479/
https://ncbi.nlm.nih.gov/pubmed/33997522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacbts.2021.01.001
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