Dynamic immune profiling identifies the stronger graft-versus-leukemia (GVL) effects with haploidentical allografts compared to HLA-matched stem cell transplantation

Haploidentical stem cell transplantation (haplo-SCT) achieves superior or at least comparable clinical outcomes to HLA-matched sibling donor transplantation (MSDT) in treating hematological malignancies. To define the underlying regulatory dynamics, we analyzed time courses of leukemia burden and im...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Mol Immunol
Prif Awduron: Guo, Huidong, Chang, Ying-Jun, Hong, Yan, Xu, Lan-Ping, Wang, Yu, Zhang, Xiao-Hui, Wang, Ming, Chen, Huan, Chen, Yu-Hong, Wang, Feng-Rong, Wei-Han, Sun, Yu-Qian, Yan, Chen-Hua, Tang, Fei-Fei, Mo, Xiao-Dong, Liu, Kai-Yan, Huang, Xiao-Jun
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2021
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8093297/
https://ncbi.nlm.nih.gov/pubmed/33408344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41423-020-00597-1
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