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High shear resistance of insect cells: the basis for substantial improvements in cell culture process design

Multicellular organisms cultivated in continuous stirred tank reactors (CSTRs) are more sensitive to environmental conditions in the suspension culture than microbial cells. The hypothesis, that stirring induced shear stress is the main problem, persists, although it has been shown that these cells...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Strobl, Florian, Duerkop, Mark, Palmberger, Dieter, Striedner, Gerald
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8093278/
https://ncbi.nlm.nih.gov/pubmed/33941799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-88813-4
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