Prognostic relevance of the hexosamine biosynthesis pathway activation in leiomyosarcoma

Metabolic reprogramming of tumor cells and the increase of glucose uptake is one of the hallmarks of cancer. In order to identify metabolic pathways activated in leiomyosarcoma (LMS), we analyzed transcriptomic profiles of distinct subtypes of LMS in several datasets. Primary, recurrent and metastat...

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Udgivet i:NPJ Genom Med
Main Authors: Tolwani, Angela, Matusiak, Magdalena, Bui, Nam, Forgó, Erna, Varma, Sushama, Baratto, Lucia, Iagaru, Andrei, Lazar, Alexander J., van de Rijn, Matt, Przybyl, Joanna
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8093268/
https://ncbi.nlm.nih.gov/pubmed/33941787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41525-021-00193-w
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