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Prognostic relevance of the hexosamine biosynthesis pathway activation in leiomyosarcoma

Metabolic reprogramming of tumor cells and the increase of glucose uptake is one of the hallmarks of cancer. In order to identify metabolic pathways activated in leiomyosarcoma (LMS), we analyzed transcriptomic profiles of distinct subtypes of LMS in several datasets. Primary, recurrent and metastat...

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Detalhes bibliográficos
Publicado no:NPJ Genom Med
Main Authors: Tolwani, Angela, Matusiak, Magdalena, Bui, Nam, Forgó, Erna, Varma, Sushama, Baratto, Lucia, Iagaru, Andrei, Lazar, Alexander J., van de Rijn, Matt, Przybyl, Joanna
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8093268/
https://ncbi.nlm.nih.gov/pubmed/33941787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41525-021-00193-w
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