Single-cell profiling reveals the trajectories of natural killer cell differentiation in bone marrow and a stress signature induced by acute myeloid leukemia

Natural killer (NK) cells are innate cytotoxic lymphoid cells (ILCs) involved in the killing of infected and tumor cells. Among human and mouse NK cells from the spleen and blood, we previously identified by single-cell RNA sequencing (scRNAseq) two similar major subsets, NK1 and NK2. Using the same...

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Vydáno v:Cell Mol Immunol
Hlavní autoři: Crinier, Adeline, Dumas, Pierre-Yves, Escalière, Bertrand, Piperoglou, Christelle, Gil, Laurine, Villacreces, Arnaud, Vély, Frédéric, Ivanovic, Zoran, Milpied, Pierre, Narni-Mancinelli, Émilie, Vivier, Éric
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8093261/
https://ncbi.nlm.nih.gov/pubmed/33239726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41423-020-00574-8
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