Single-cell profiling reveals the trajectories of natural killer cell differentiation in bone marrow and a stress signature induced by acute myeloid leukemia

Natural killer (NK) cells are innate cytotoxic lymphoid cells (ILCs) involved in the killing of infected and tumor cells. Among human and mouse NK cells from the spleen and blood, we previously identified by single-cell RNA sequencing (scRNAseq) two similar major subsets, NK1 and NK2. Using the same...

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Publicado en:Cell Mol Immunol
Autores principales: Crinier, Adeline, Dumas, Pierre-Yves, Escalière, Bertrand, Piperoglou, Christelle, Gil, Laurine, Villacreces, Arnaud, Vély, Frédéric, Ivanovic, Zoran, Milpied, Pierre, Narni-Mancinelli, Émilie, Vivier, Éric
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8093261/
https://ncbi.nlm.nih.gov/pubmed/33239726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41423-020-00574-8
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