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The Promises and Limitations of N-Acetylcysteine as a Potentiator of First-Line and Second-Line Tuberculosis Drugs

N-Acetylcysteine (NAC) is most commonly used for the treatment of acetaminophen overdose and acetaminophen-induced liver injury. In patients infected with Mycobacterium tuberculosis, the causative agent of tuberculosis (TB), NAC is given to treat hepatotoxicity induced by TB drugs. We had previously...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Vilchèze, Catherine, Jacobs, William R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8092890/
https://ncbi.nlm.nih.gov/pubmed/33619056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01703-20
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