Mutations in PB1, NP, HA, and NA Contribute to Increased Virus Fitness of H5N2 Highly Pathogenic Avian Influenza Virus Clade 2.3.4.4 in Chickens

The H5N8 highly pathogenic avian influenza (HPAI) clade 2.3.4.4 virus spread to North America by wild birds and reassorted to generate the H5N2 HPAI virus that caused the poultry outbreak in the United States in 2015. In previous studies, we showed that H5N2 viruses isolated from poultry in the late...

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Bibliographic Details
Published in:J Virol
Main Authors: Youk, Sung-Su, Leyson, Christina M., Seibert, Brittany A., Jadhao, Samadhan, Perez, Daniel R., Suarez, David L., Pantin-Jackwood, Mary J.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2021
Subjects:
Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8092828/
https://ncbi.nlm.nih.gov/pubmed/33268526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01675-20
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